Other name : Dehydroepiandrosteron acetate (DHA); 5-Epiandroster-17-one acetate ; DHE-A Acetate.
CAS register number : 53-43-0
Molecular formula : C21H30O3
Molecular weight : 330.4611
Assay : Above 99.3%
Usage : pharmaceutical material, Steroid hormone, Anabolin1-DHEA is a prohormone to 1-Testosterone (dihydroboldenone). It is commonly sold under the brand name of “1-Andro” (1-Androsterone). 1-Andro is a non 17-aa prohormone requiring two steps in its conversion to 1-Test. Reduction of the 17-ketone functional group by 17b-HSD produces 1-Androstenediol while oxidation of the 3-hydroxyl group by 3a-HSD produces 1-Androstenedione. Both of these metabolites may have some intrinsic anabolic/androgenic properties, but it is their further conversion to 1-Testosterone that produces the anabolic muscle building effects seen from 1-Andro.1-Andro appears weak structurally. It requires two enzymatic conversions to become the target hormone 1-Testosterone. Throw in the fact that it is technically a “DHEA” molecule, and most would believe it to be weak prohormone. However, a new study performed by West Texas A&M University shows otherwise.
9 males with an average of 5 years experience in resistance training and an average bodyfat of 13% were given 330 mg of 1-Andro daily for 4 weeks while completing a structured resistance training program. Data was collected pre-cycle and post-cycle on: lean mass, strength, lipids, and cardiac metabolic function. Studies like these are the holy grail of prohormone studies. They are very rare. When a study like this is performed on a prohormone, it is wise to Any diet measured in hours can’t be all that bad, right? Two days is all they’re asking for here, which can be planned around your weekend so you don’t have to try to while you’re on the go. take notice. These studies give better answers to the overly common questions of what kind of gains one can expect, what dose is best, and the degree of toxicity that comes from the prohormone.Results showed 1-Andro to be significantly more powerful than it would appear structurally. The 9 males gained an average lean mass of 10.4 lbs and an increase in strength of 92.2 lbs in total load on bench/squat/deadlift. These are significant gains from a prohormone. It is important to keep in mind that these results were seen from 330 mg of pure 1-Andro taken daily. The recommended dosages on the internet vary from 100-800 mg per day; obviously 800 mg being excessive in retrospect to this study. It was interesting to note that cardiac metabolic function was negatively affected as evident by the increase in creatinine and aspartate transaminase (AST). Lipids were also negatively effected; an increase in LDL and decrease in HDL were observed.
1- Androsteronetm (1-DHEA) is a non-methylated (non 17aa) pro-steroid that must convert to 1-androstenediol (1-AD), 1-androstenedione (original 1-AD) and/or 1-testosterone to be active. The double bond in the 1st position seems to slightly enhance its ability to resist excretion by the liver.
1-Androsterone occurs naturally in the body, and is a naturally occurring metabolite of DHEA. (2) The 17b-HSD enzyme converts 1-Androsterone to 1-Androstenediol, and the 3b-HSD converts it to 1-Androstenedione. Both of these 1-AD metabolites can then be converted to 1-Testosterone. Although the 1-AD metabolites are known to have some anabolic and androgenic effects on their own, 1-Testosterone is probably where most of the effects come from with this steroid.
There is no conversion to estrogen so users will not experience bloat with this compound, nor will it have a dramatic effect on blood pressure. However one unique side effect that users have reported with this compound is a feeling of lethargy. (It appears that stacking 1-Androsterone with a nuero-active hormone such as DHEA can help reverse this effect).
1-Androsterone (and primarily its metabolites) have relatively potent androgenic effects, therefore gyno is almost never an issue. However, because of the androgenic potency, this compound could pose a mild hair loss risk for those prone to MPB. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.
Results from this compound generally take a couple weeks to be realized. Moderate gains of lean muscle mass and strength can be expected, but users should not expect rapid increases in size or weight with this compound since extra-cellular and intra-cellular water retention are very minimal. This makes the gains from this steroid fairly easy to maintain post cycle.
1-Androsterone will stack well with almost any compound. For more dramatic gains in size and strength it is recommended to stack this compound with an aromatizing steroid or possibly one of the progestational compounds listed elsewhere.
The dosing one chooses to work with varies greatly on whether they are stacking this compound with other anabolics or running it solo. Generally with 1-DHEA 300-600mg a day is the most popular dosage, however experienced users with past pro-hormone or designer steroid experience can experiment with dosages in upwards of 700-1000mg. The added benefit may be negligible at this dosage and the likely-hood of side effects sharply increases..
Since this compound is not as hard on your body cycles can be extended up to 8 weeks in length with 6 weeks being the most common. Most users will begin to notice the effects by the third week in the form of muscle hardness/increased strength. Novice users should always stay within the general dosing amounts and not exceed 6 weeks in cycle length, although more experienced users can safely run 1-DHEA for 8 weeks.
You should split up your dosages into 2-3 different times throughout the day, ideally separated by 5-6 hours (or 8 hours if two daily dosages). For the ideal results, take your largest dosage 45 minutes to one hour before your workout session.
Decreased Libido/Sexual Function
Anxiety / Stimulated Feeling
Slightly increased Blood Pressure
Back Pumps (Dull pain in back after/during workouts)
1-DHEA is a popular stacker, this is because it’s relatively mild and non-methylated which allows users to stack this substance with popular methylated anabolics such as Halodrol. Typically users would want to stack this compound with lower androgenicl substances to provide a balanced anabolic/androgenic effect. 1-DHEA can be utilized during either a bulk or a cut. Below is a short list of several anabolics 1-DHEA is commonly stacked with:
Methylated Compounds (H-Drol, P-mag, Superdrol, etc)
Non-Methylated Compounds (11-OXO, 4-DHEA, Furazadrol, M-LMG, etc)
Post Cycle Therapy
Post cycle therapy is, as always, one of the most important parts of any cycle. If one does not work towards bringing their body back to homeostasis gains will be lost (making the health risks pointless) and the chance for side effects increases significantly. Once you stop taking a designer steroid or pro-hormone your body goes through a change of hormones and puts stress on your endocrine system. With a properly planned PCT (Post Cycle Therapy) we assist our body with easing back into normal function. Failure to follow a properly planned PCT can result in undesirable side effects such as:
Gynecomastia (Bitch Tits)
Muscle Loss/Fat Gain