Description
Introduction:
Product Name: MK-677
Synonyms: Ibutamoren
CAS: 159752-10-0
MF: C28H40N4O8S2
MW: 624.77
Bp: 868.9 °C at 760 mmHg
Fp: 479.3 °C
Specific optical rotation: +79.3°
Loss on drying: 0.15%
Free heptanoic acid: 0.10%
Related substances: ≤2%
Appearance: white powder
Package: 1g; 10g; 100g; 500g; 1kg
Storage: At room temperature
Application:
MK-677 is an orally administrated growth / hormone secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete . In other words, MK-677 could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn’t require any injections nor does it have any side effects like GHRP-6. This GHS (Growth / Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety
Usage:
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the
bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARd agonist. Exhibits selectivity for PPARd compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
Benefits:
In a study on it’s effects on catabolic states, a once daily oral dose of 25mgs was given to healthy young men subjected to short-term diet-induced nitrogen wasting. After 7 days of this dose, the subjects showed a sustained increase in serum concentration of IGF-1 and Growth Hormone; in addition, the nitrogen wasting was reversed, showing great potential for treatment of conditions involving muscle wasting.
A study done for the treatment of osteoporosis and bone mineral density showed some increase in bone density, so there is a true impact on bone mineral density. This can help with injury recovery during your cycle.
Detection Result:
Product | Mk-677 | CAS No. | 159752-10-0 |
Batch No. | 20160410 | Man.date | 2016-04-12 |
Testing date | 2016-04-13 | Expiry date | 2018-04-11 |
Items | Specifications | Results | |
Description | White powder | White powder | |
Content | ≥99.0% | 99.36% | |
Specific Rotation | -15.71 | -15.9 | |
Loss on Drying | ≤1.0% | 0.4% | |
Conclusion : The product meets In-house specifications |
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